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Circulating and exhaled vascular endothelial growth factor in asthmatic pregnancy
Andras Bikov1, Aniko Bohacs, Noemi Eszes
1Department of Pulmonology, Semmelweis University, Budapest, Hungary.
Context:
Vascular endothelial growth factor (VEGF) plays a role in asthma and pathological pregnancies.
Objective:
This is the first study assessing plasma and exhaled breath condensate VEGF levels in asthmatic pregnancy.
Material And Methods:
Thirty-one asthmatic pregnant, 29 asthmatic nonpregnant, 28 healthy pregnant and 22 healthy nonpregnant women were enrolled. Plasma was collected in all subjects, EBC in 57 volunteers for VEGF measurements.
Results:
Plasma VEGF decreased in both pregnant groups (p < 0.01), without any differences between the asthmatic and the respective nonasthmatic groups (p > 0.05). VEGF was undetectable in EBC.
Conclusion:
Concomitant asthma does not affect plasma VEGF during pregnancy.
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