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Cardiac manifestations of cutaneous disorders
Jenna L O'Neill1, Swetha Narahari, David C Sane
1Department of Dermatology, Wake Forest University School of Medicine, Winston-Salem, North Carolina 27157-1071, USA.
Insights
Dermatologists can identify skin conditions linked to heart problems. Early recognition of these cutaneous disorders aids in diagnosing underlying cardiovascular disease.
Area of Science:
- Dermatology
- Cardiology
- Genetics
Background:
- Cutaneous and cardiovascular systems share common genetic linkages and pathological processes.
- Dermatologists frequently encounter skin disorders with potential cardiac implications.
Purpose of the Study:
- To review primary cutaneous disorders with cardiac manifestations.
- To highlight the importance of dermatologists recognizing skin findings associated with cardiovascular disease.
Main Methods:
- Literature review of genetic linkages between cutaneous and cardiovascular systems.
- Categorization of cutaneous disorders based on cardiac associations (congenital, later disease, early pathology).
Main Results:
- Identified genetic links between skin and heart conditions.
- Detailed primary cutaneous disorders with potential cardiac involvement.
- Emphasized the dermatologist's role in early diagnosis.
Conclusions:
- Awareness of cutaneous-cardiac associations is crucial for dermatologists.
- Dermatological diagnosis can prompt essential cardiovascular workup.
- Interdisciplinary understanding improves patient outcomes for related conditions.
Abstract:
A number of cutaneous disorders encountered by the dermatologist have overlapping cardiac pathology. In recent years, many genetic linkages common to pathological processes in the cutaneous and cardiovascular systems have been identified. This review will describe primary cutaneous disorders with potential cardiac manifestations, including congenital syndromes, inherited cutaneous disorders associated with later cardiovascular disease, and syndromes associated with early cardiovascular pathology. The dermatologist may be the first to diagnose cutaneous findings associated with underlying cardiovascular disease; therefore, it is of prime importance for the dermatologist to be aware of these associations and to direct the appropriate workup.
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