[Aerosol generators and the determination of their aerosol size distribution]

To determine aerosol size distribution of several particle generators for the inhalation therapy we employed a laser scattering method and QCM cascade impactor method. The particle size distribution measured by the latter method showed MDI less than Diskhaler less than Jet nebulizer, the smaller in order. Our model analysis also suggests that an usage of a spacer (especially the size of around 150 ml) enable to increase the total amount of aerosol inhalation into the lungs, when MDI is applied as an aerosol generator.