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In Vitro Ubiquitination and Deubiquitination Assays of Nucleosomal Histones
11:36

In Vitro Ubiquitination and Deubiquitination Assays of Nucleosomal Histones

Published on: July 25, 2019

A conserved deubiquitinating enzyme controls cell growth by regulating RNA polymerase I stability

Lauren A Richardson1, Benjamin J Reed, J Michael Charette

  • 1Department of Pharmacology, University of Washington, Seattle, 98195, USA.

Cell Reports
|August 21, 2012
PubMed
Summary

The yeast deubiquitinating enzyme Ubp10 regulates ribosome production by stabilizing RNA polymerase I. This deubiquitination process is conserved in humans, highlighting its importance in eukaryotic cell growth.

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