[First-time occurring angina pectoris: dynamics of coronary artery stenosis during a 1-year follow-up]

Thirty patients with first angina (FA) underwent repeated coronary angiographic examinations in the first 3 months of the disease and 15.0 +/- 3.1 (M +/- sigma) after. At the second coronary angiography, 9 (30%) patients developed a clinical remission. The time course of stenoses was assessed by a quantitative method such as the vessel contour outline one. Six (20%) patients displayed stenosis regression, 5 (17%) had both regression and progression, 11 (37%) exhibited progression, 8 (26%) showed no changes. The multifactorial discriminant step-by-step analysis was employed to assess the predictive value of various clinical, bicycle ergometric, lipid, and angiographic factors in the time course of stenoses. In the first year of the follow-up, stenosis regression was seen in 20% of the FA patients. By the second coronary angiography, the patients with remained angina showed a high probability that there had been a progression of at least one stenosis. The probability was also high in patients with less obesity, a greater number of affected vessels and a more severity of the disease in the first month.