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Bilateral ulna fractures associated with bisphosphonate therapy
Summary
Long-term bisphosphonate use may be linked to bilateral ulna stress fractures in elderly women, even without other bone loss risk factors. Stopping the medication and conservative treatment were initiated for this rare case.
Area of Science:
- Orthopedics
- Pharmacology
- Geriatrics
Background:
- Bisphosphonates are commonly prescribed for osteoporosis and bone metastasis.
- Long-term use can lead to atypical bone fractures.
- Elderly patients with reduced mobility are a key demographic.
Observation:
- An 84-year-old woman with 15 years of bisphosphonate therapy presented with atraumatic bilateral ulna pain.
- She had a history of bilateral femoral fractures.
- No other risk factors for bone loss were identified.
Findings:
- Bilateral ulna stress fractures were diagnosed.
- The patient's bisphosphonate therapy was discontinued.
- Conservative management with backslabs was implemented.
Implications:
- This case highlights a potential, rare complication of long-term bisphosphonate therapy.
- It suggests the need for vigilance regarding atypical fractures in patients on prolonged bisphosphonate treatment.
- Further research into the mechanisms and incidence of such fractures is warranted.
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