[The dynamic activity of lymphocyte succinate dehydrogenase and its correlations in experimental malaria]

Succinic dehydrogenase (SDH) activity in peripheral blood lymphocytes has been studied in progressing experimental malaria on a P. yoelii model, the strain 265 BY; the multinipple rats Mastomys natalensis. Cytochemical method employing n-nitrotetrazolium violet was used. Comparative analysis of changes in SDG activity in peripheral blood lymphocytes and changes in the level of parasitemia has demonstrated that day 10 was a critical period when there was an evident inverse correlation between the qualitative parameters. The findings give evidence of SDH participation in an adequate response of immunocompetent cells to malaria infection, thus leading to recovery.