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Related Experiment Videos

[Molecular drive].

M V Vol'kenshteĭn

    Molekuliarnaia Biologiia
    |September 1, 1990
    PubMed
    Summary
    This summary is machine-generated.

    Molecular drive, a non-Mendelian evolutionary process, involves gene duplication and non-coding DNA. This mechanism, including gene conversion and transposition, drives speciation and macroevolution.

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    [Neutral mutations and interference-stability of the genetic code].

    Molekuliarnaia biologiia·1988

    Area of Science:

    • Evolutionary biology
    • Molecular genetics

    Context:

    • Review of concepts in molecular evolution.
    • Focus on non-coding DNA and gene duplication.

    Purpose:

    • To present the concept of molecular drive.
    • To characterize gene duplication as a precursor to new gene function.
    • To examine non-Mendelian genetic processes.

    Summary:

    • Molecular drive integrates non-equal crossing-over, gene conversion, and gene transposition.
    • Examples of molecular drive are provided.
    • This mechanism is linked to genome instability and evolution.

    Impact:

    • Molecular drive is proposed as a fundamental mechanism for speciation and macroevolution.
    • It suggests that molecular evolution is non-Mendelian and non-Darwinian.
    • Both coding and non-coding DNA can be substrates for evolutionary change.