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[Severe liver involvement by Capillaria hepatica].

J Pannenbecker1, T C Miller, J Müller

  • 1Kinderklinik und Kinderpoliklinik, Universität Würzburg.

Monatsschrift Kinderheilkunde : Organ Der Deutschen Gesellschaft Fur Kinderheilkunde
|November 1, 1990
PubMed
Summary
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Human hepatic capillariasis, a rare parasitic infection primarily affecting young children, presents with severe symptoms like fever and liver enlargement. This case report details a successful treatment approach in Germany using Thiabendazole and Ivermectin.

Area of Science:

  • Parasitology
  • Pediatric Hepatology
  • Tropical Medicine

Context:

  • Human hepatic capillariasis is a rare parasitic disease predominantly affecting children aged 1-4 years.
  • This is the first documented case of human hepatic capillariasis in Germany.
  • The infection has a poor prognosis in extensive cases, characterized by severe parasitosis symptoms.

Purpose:

  • To report the first case of human hepatic capillariasis in Germany.
  • To describe the clinical presentation, diagnosis, and treatment of this rare condition in a pediatric patient.
  • To highlight a potential therapeutic strategy for this challenging disease.

Summary:

  • The case involved an 18-month-old girl presenting with persistent high fever, hepatomegaly, and extreme hypereosinophilia, indicative of severe parasitosis.

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  • Diagnosis was confirmed via liver biopsy, revealing intracellular Capillaria eggs.
  • The patient developed liver fibrosis and was treated with high-dose Thiabendazole, two doses of Ivermectin, and Decortin to manage granulomatous inflammation, leading to survival.

    • Impact:

    • This report expands the geographical understanding of human hepatic capillariasis.
    • It provides valuable insights into the clinical management and therapeutic outcomes for a rare pediatric liver disease.
    • The successful treatment regimen may inform future clinical practice for similar cases.