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Updated: May 19, 2026

Preparation and In Vivo Use of an Activity-based Probe for N-acylethanolamine Acid Amidase
Published on: November 23, 2016
(E)-4-Amino-N'-(2-hy-droxy-5-meth-oxy-benzyl-idene)benzohydrazide monohydrate
Abstract:
In the title compound, C(15)H(15)N(3)O(3)·H(2)O, the hydazide Schiff base mol-ecule shows an E conformation around the C=N bond. An intra-molecular O-H⋯N hydrogen bond makes an S(6) ring motif. The dihedral angle between the substituted phenyl rings is 23.40 (11)°. The water mol-ecule mediates linking of neighbouring mol-ecules through O-H⋯(O,O) hydrogen bonds into infinite chains along the a axis, which are further connected together through N-H⋯O hydrogen bonds, forming a two-dimensional network parallel to (001). C-H⋯O inter-actions aso occur.
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