Related Experiment Video

Updated: May 19, 2026

Cercosporin-Photocatalyzed [4+1]- and [4+2]-Annulations of Azoalkenes Under Mild Conditions
07:12

Cercosporin-Photocatalyzed [4+1]- and [4+2]-Annulations of Azoalkenes Under Mild Conditions

Published on: July 17, 2020

(Z)-1-(2-Chloro-phen-yl)-3-methyl-4-[2-(4-nitro-phen-yl)hydrazin-1-yl-idene]-1H-pyrazol-5(4H)-one

Carlos Bustos, Andrés Escobar-Fuentealba, Luis Alvarez-Thon

    Acta Crystallographica. Section E, Structure Reports Online
    |August 21, 2012
    PubMed

    More Related Videos

    Facile Preparation of (2Z,4E)-Dienamides by the Olefination of Electron-deficient Alkenes with Allyl Acetate06:46

    Facile Preparation of (2Z,4E)-Dienamides by the Olefination of Electron-deficient Alkenes with Allyl Acetate

    Published on: June 21, 2017

    Microwave-Assisted Preparation of 1-Aryl-1H-pyrazole-5-amines05:07

    Microwave-Assisted Preparation of 1-Aryl-1H-pyrazole-5-amines

    Published on: June 23, 2019

    Related Concept Videos

    Hydrolysis of Chlorobenzene to Phenol: Dow Process01:10

    Hydrolysis of Chlorobenzene to Phenol: Dow Process

    Simple aryl halides do not react with nucleophiles under normal conditions. However, the reaction can proceed under drastic conditions involving high temperatures and high pressure to give the substituted products. For example, chlorobenzene is converted to phenol using aqueous sodium hydroxide at 350 °C under high pressure by the Dow process. The reaction follows an elimination-addition mechanism involving a benzyne intermediate. Here, the chloride ion is eliminated to generate the benzyne...
    Diazonium Group Substitution: –OH and –H01:19

    Diazonium Group Substitution: –OH and –H

    Nitrous acid, a weak acid, is prepared in situ via the reaction of sodium nitrite with a strong acid under cold conditions. This nitrous acid prepared in situ reacts with primary arylamines to form arenediazonium salts. Such reactions are known as diazotization reactions. As shown in Figure 1, the formation of arenediazonium salts begins with the decomposition of nitrous acid in an acidic solution to give nitrosonium ions.
    Nucleophilic Aromatic Substitution of Aryldiazonium Salts: Aromatic SN101:14

    Nucleophilic Aromatic Substitution of Aryldiazonium Salts: Aromatic SN1

    Treating arylamines with nitrous acid gives aryldiazonium salts that are effective substrates in nucleophilic aromatic substitution reactions. The diazonio group in these salts can be easily displaced by different nucleophiles, yielding a wide variety of substituted benzenes. The leaving group departs as nitrogen gas, and this easy elimination is the driving force for the substitution reaction.
    In the Sandmeyer reaction, for example, the diazonio group is replaced by a chloro, bromo, or cyano...
    Nomenclature of Aromatic Compounds with Multiple Substituents01:11

    Nomenclature of Aromatic Compounds with Multiple Substituents

    When more than one substituent is present on the benzene ring, the IUPAC nomenclature depends on the number of substituents present.
    For disubstituted benzene derivatives, with two groups attached to the benzene ring, three constitutional isomers are possible. For example, consider dimethyl benzene, often called xylene, where the second methyl group can be substituted at the second, third, or fourth carbon. The relative position of the substituents is represented by prefixes ortho, meta, or...
    Diazonium Group Substitution with Halogens and Cyanide: Sandmeyer and Schiemann Reactions01:20

    Diazonium Group Substitution with Halogens and Cyanide: Sandmeyer and Schiemann Reactions

    Arenediazonium substitution reactions occur when the diazonium group is substituted by various functional groups such as halides, hydroxyl, nitrile, etc. For instance, arenediazonium salts react with copper(I) salts of chloride, bromide, or cyanide to form corresponding aryl chlorides, bromides, and nitriles. These reactions are named Sandmeyer reactions. Although the mechanism of this reaction is complicated, as illustrated in Figure 1, they are believed to progress via an aryl copper...
    Structure and Nomenclature of Alcohols and Phenols02:23

    Structure and Nomenclature of Alcohols and Phenols

    Overview
    Alcohols are one of the most important functional groups in organic chemistry. The name of alcohol comes from the hydrocarbon from which it is derived. Alcohols are organic molecules containing the functional hydroxyl or –OH group directly bonded to carbon. Phenols have an OH group directly attached to a benzene ring. While alcohols are colorless, phenol is a white crystalline compound with a characteristic "hospital smell" odor.
    As with other organic compounds, alcohols and phenols...