N-(4-Chloro-phen-yl)-2,2-diphenyl-acetamide

Area of Science:

• Crystallography
• Organic Chemistry
• Supramolecular Chemistry

Background:

• Understanding molecular interactions and crystal packing is crucial in materials science and drug design.
• Intramolecular and intermolecular forces dictate the solid-state properties of organic compounds.

Purpose of the Study:

• To elucidate the crystal structure of the title compound C(20)H(16)ClNO.
• To analyze the hydrogen bonding network and intermolecular interactions within the crystal lattice.

Main Methods:

• Single-crystal X-ray diffraction was employed to determine the molecular and crystal structure.
• Analysis of bond distances, angles, and dihedral angles provided insights into molecular geometry.
• Intermolecular interactions, including hydrogen bonds and C-H⋯π interactions, were identified and characterized.

Main Results:

• The title compound exhibits an S(6) ring motif formed by an intramolecular C-H⋯O hydrogen bond.
• The chloro-substituted benzene ring is nearly perpendicular to the other benzene rings, with dihedral angles around 87-89°.
• Molecules are arranged in chains along the c-axis via intermolecular N-H⋯O hydrogen bonds.
• Weak C-H⋯π interactions involving the chloro-substituted ring contribute to the crystal packing.

Conclusions:

• The crystal structure of C(20)H(16)ClNO is characterized by specific intramolecular and intermolecular interactions.
• The observed hydrogen bonding and π-interactions influence the overall molecular arrangement and stability in the solid state.
• This structural information contributes to the understanding of structure-property relationships in related organic compounds.