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Visceral leishmaniasis: A case report.
Sachin Gawade1, Mangesh Nanaware, Rm Gokhale
1Department of Community Medicine [PSM], B.J. Medical College,Sassoon General Hospital, Pune, Maharashtra, India.
The Australasian Medical Journal
|August 21, 2012
Summary
Diagnosing visceral leishmaniasis (kala-azar) in India remains challenging. This case highlights successful diagnosis via bone marrow aspiration and treatment with amphotericin B, improving patient outcomes.
Area of Science:
- Medical Parasitology
- Infectious Diseases
- Public Health
Background:
- Visceral leishmaniasis (kala-azar) is endemic in eastern India, posing diagnostic challenges.
- Early diagnosis and treatment are crucial for managing this parasitic disease.
Observation:
- A 20-year-old presented with prolonged fever, weakness, abdominal discomfort, and petechial hemorrhages.
- Physical examination revealed hepatosplenomegaly, indicative of visceral leishmaniasis.
Findings:
- Bone marrow aspiration cytology confirmed visceral leishmaniasis (kala-azar).
- Routine blood tests showed pancytopenia; chest X-ray was unremarkable.
- Intravenous amphotericin B treatment led to a favorable clinical response.
Implications:
- This case underscores the importance of bone marrow aspiration in diagnosing challenging kala-azar cases.
- Effective treatment with amphotericin B offers a positive prognosis for visceral leishmaniasis patients.
- Improved diagnostic strategies are needed for widespread kala-azar detection in endemic regions.

