Related Experiment Video
Updated: May 19, 2026

A Method to Study the C924T Polymorphism of the Thromboxane A2 Receptor Gene
Published on: April 1, 2019
jPopGen Suite: population genetic analysis of DNA polymorphism from nucleotide sequences with errors
1Human Genetics Center, School of Public Health, The University of Texas Health Science Center at Houston, 1200 Herman Pressler Drive, Houston, TX 77030, USA.
None:
1. Next-generation sequencing (NGS) is being increasingly used in ecological and evolutionary studies. Though promising, NGS is known to be error-prone. Sequencing error can cause significant bias for population genetic analysis of a sequence sample.2. We present jPopGen Suite, an integrated tool for population genetic analysis of DNA polymorphisms from nucleotide sequences. It is specially designed for data with a non-negligible error rate, although it serves well for "error-free" data. It implements several methods for estimating the population mutation rate, population growth rate, and conducting neutrality tests.3. jPopGen Suite facilitates the population genetic analysis of NGS data in various applications, and is freely available for non-commercial users at http://sites.google.com/site/jpopgen/.
Related Concept Videos
Genetic Variation
Genes exist in different versions called alleles, which...
Single Nucleotide Polymorphisms-SNPs
Mutation, Gene Flow, and Genetic Drift
What is Population Genetics?
Genome Copying Errors
Gene Duplication and Divergence
The duplicated copies of the gene are called Paralogs. Paralogs with similar sequences and functions form a gene family. Across several species, a large number of gene families are characterized.

