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Preparation of Tumor Antigen-loaded Mature Dendritic Cells for Immunotherapy
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Published on: August 1, 2013

Dendritic cells as natural adjuvants and modulators of immune response in cancer immunotherapy

Rajshekhar S Alli1, Ashok Khar

  • 1Centre for Cellular & Molecular Biology, Uppal Road, Hyderabad 500 007, India.

Indian Journal of Biochemistry & Biophysics
|August 22, 2012
PubMed

Dendritic cells (DCs) are potent antigen presenting cells. Mature DCs activate antigen specific naïve T cells, B cells and NK cells. Under certain conditions, DCs even silence T cell immune responses in vivo, thus, modulating the immune response. This special function of DCs could be exploited in the treatment of cancer, autoimmune disorder and chronic viral infections.

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