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Updated: May 19, 2026
Induction and Analysis of Oxidative Stress in Sleeping Beauty Transposon-Transfected Human Retinal Pigment Epithelial Cells
Published on: December 11, 2020
Selenium modulates oxidative stress-induced TRPM2 cation channel currents in transfected Chinese hamster ovary cells
Mustafa Nazıroğlu1, Cemil Özgül, Mustafa Küçükayaz
1Department of Biophysics, Medical Faculty, Süleyman Demirel University, Isparta, Turkey. mustafanaziroglu@sdu.edu.tr
Abstract:
It has been recently reported that the essential antioxidant element selenium has protective effects on cytosolic Ca(2+) levels in cell lines. However, the effects of selenium on like transient receptor potential melastatin 2 (TRPM2) in response to oxidative stress (H(2) O(2) ) are not well understood. We investigated the effects of selenium on H(2) O(2) -induced TRPM2 channel currents in the Chinese hamster ovary (CHO) cell line using patch-clamp and fura-2 fluorescence imaging techniques.
