Irrigation with bupivacaine at the surgical bed for postoperative pain relief after laparoscopic cholecystectomy
Gerardo Castillo-Garza1, José A Díaz-Elizondo, Carlos A Cuello-García
1General Surgery, Tecnologico de Monterrey-Escuela de Medicina y Ciencias de la Salud. Postgraduate Area, Monterrey, N. L. México. dr.gcg@hotmail.com
Purpose:
The aim of this study was to evaluate the effect of bupivacaine irrigated at the surgical bed on postoperative pain relief in laparoscopic cholecystectomy patients.
Methods:
This study included 60 patients undergoing elective laparoscopic cholecystectomy who were prospectively randomized into 2 groups. The placebo group (n=30) received 20cc saline without bupivacaine, installed into the gallbladder bed. The bupivacaine group (n=30) received 20cc of 0.5% bupivacaine in at the same surgical site. Pain was assessed at 0, 6, 12, and 24 hours by using a visual analog scale (VAS).
Results:
A significant difference (P=.018) was observed in pain levels between both groups at 6 hours postoperatively. The average analgesic requirement was lower in the bupivacaine group, but this did not reach statistical significance.
Conclusions:
In our study, the use of bupivacaine irrigated over the surgical bed was an effective method for reducing pain during the first postoperative hours after laparoscopic cholecystectomy.
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