Related Experiment Video

Updated: May 19, 2026

Vessel-sparing Excision and Primary Anastomosis
08:09

Vessel-sparing Excision and Primary Anastomosis

Published on: January 7, 2019

Clinical outcomes and long-term resolution in patients with persistent vesicoureteral reflux after open ureteral

Katherine C Hubert1, Paul J Kokorowski, Lin Huang

  • 1Department of Urology, Children's Hospital Boston, Boston, Massachusetts 02115, USA.

The Journal of Urology
|August 22, 2012
PubMed

Insights

Most children with persistent vesicoureteral reflux after ureteral reimplantation experience spontaneous resolution. Nonoperative management offers good long-term outcomes for this condition.

Area of Science:

  • Pediatric Urology
  • Nephrology
  • Surgical Outcomes

Background:

  • Ureteral reimplantation is a common procedure for primary vesicoureteral reflux.
  • Data on the long-term natural history and resolution rates of persistent vesicoureteral reflux post-reimplantation is limited.

Purpose of the Study:

  • To evaluate the clinical outcomes and long-term resolution of persistent vesicoureteral reflux in children following ureteral reimplantation.
  • To understand the natural history of persistent vesicoureteral reflux after surgical intervention.

Main Methods:

  • Retrospective review of children with persistent vesicoureteral reflux (grade 1 or greater) after ureteral reimplantation (1990-2002).
  • Analysis of subsequent cystograms, surgical interventions, and urinary tract infections.
  • Survival analysis was performed to determine the time to resolution for persistent and clinically significant reflux.

Main Results:

  • 6.1% of 965 patients (59 children) had persistent vesicoureteral reflux post-reimplantation.
  • Spontaneous resolution occurred in 72.2% of patients with persistent reflux (median 20.4 months).
  • 13% experienced postoperative febrile urinary tract infections; one patient required repeat reimplantation.

Conclusions:

  • Persistent vesicoureteral reflux after ureteral reimplantation often resolves spontaneously in pediatric patients.
  • Nonoperative management is a viable strategy for persistent vesicoureteral reflux, leading to favorable long-term outcomes.
Abstract

Related Concept Videos

Kidney Transplant II: Surgical Procedure01:26

Kidney Transplant II: Surgical Procedure

Preoperative ManagementThe primary goals of preoperative management in kidney transplantation are to optimize the patient’s metabolic state and prepare them for surgery through diet adjustments, necessary dialysis, and tailored medical treatment. This phase also involves comprehensive infection screening and patient education about the surgical procedure and postoperative care to improve outcomes and adherence.Medical ManagementA comprehensive evaluation is required for both the living donor...
Urinary Tract Calculi VI: Surgical Management01:25

Urinary Tract Calculi VI: Surgical Management

Procedures for Kidney StonesMedical intervention is necessary when kidney stones or renal calculi are too large to pass spontaneously (typically greater than 5 millimeters) when stones are accompanied by symptomatic infection (such as fever or pyelonephritis), when they impair kidney function, or when they cause persistent symptoms like severe pain, nausea, or urinary retention. Additionally, patients with only one kidney or those who cannot be treated with medical management also require...
Acute Kidney Injury III: Clinical Manifestations01:29

Acute Kidney Injury III: Clinical Manifestations

Acute Kidney Injury (AKI) progresses through distinct clinical phases: the oliguric, diuretic, and recovery phases, each marked by unique manifestations and challenges.Oliguric Phase:The oliguric phase is the initial stage of AKI, typically lasting 10 to 14 days. This phase is marked by a significant reduction in urine output, usually less than 400 mL per day, indicating decreased kidney function. Fluid retention is a prominent feature, leading to symptoms such as edema, hypertension, and...
Imaging Studies V: Intravenous Urography and Retrograde Pyelography01:22

Imaging Studies V: Intravenous Urography and Retrograde Pyelography

IntroductionIntravenous Urography (IVU) and Retrograde Pyelography (RP) are important diagnostic imaging techniques used to evaluate the urinary system. These methods help identify structural abnormalities, obstructions, and functional issues in the kidneys, ureters, and bladder. Both procedures use iodine-based contrast media to enhance the visibility of urinary tract structures on X-ray images, though they differ in their methods and indications.1. Intravenous Urography (IVU)Intravenous...
Imaging Studies VI: Voiding Cystourethrography and Cystography01:22

Imaging Studies VI: Voiding Cystourethrography and Cystography

Voiding Cystourethrography (VCUG) and Cystography are specialized radiographic procedures used to examine the structure and function of the bladder and urethra.Voiding Cystourethrography (VCUG)A Voiding Cystourethrogram (VCUG) is a diagnostic imaging procedure that assesses the anatomy and function of the lower urinary tract. It focuses on the bladder, bladder neck, and urethra, helping detect abnormalities such as vesicoureteral reflux (VUR)—the backward or reverse flow of urine into the...
Urologic Endoscopic Procedure: Cystoscopic Examination01:28

Urologic Endoscopic Procedure: Cystoscopic Examination

Meaning of Cystoscopic Examination:Cystoscopy is an essential diagnostic tool in urology that is used to assess the structure and function of the genitourinary system. It provides a direct view of the urethra, bladder, and, in some cases, the ureteral openings. This procedure helps detect structural abnormalities, infections, cancers, and blockages in the urinary tract. There are two types of cystoscopy:Flexible cystoscopy is commonly performed in outpatient settings due to its less invasive...