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Targeted Cancer Therapies

Targeted Cancer Therapies

The targeted cancer therapies, also known as “molecular targeted therapies,” take advantage of the molecular and genetic differences between the cancer cells and the normal cells. It needs a thorough understanding of the cancer cells to develop drugs that can target specific molecular aspects that drive the growth, progression, and spread of cancer cells without affecting the growth and survival of other normal cells in the body.
There are several types of targeted therapies against specific...

Targeted Cancer Therapies

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Related Experiment Video

Updated: May 19, 2026

Surface-enhanced Resonance Raman Scattering Nanoprobe Ratiometry for Detecting Microscopic Ovarian Cancer via Folate Receptor Targeting

Surface-enhanced Resonance Raman Scattering Nanoprobe Ratiometry for Detecting Microscopic Ovarian Cancer via Folate Receptor Targeting

Published on: March 25, 2019

Challenges to effective cancer nanotheranostics.

Marites P Melancon¹, R Jason Stafford, Chun Li

¹Department of Experimental Diagnostic Imaging, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.

Journal of Controlled Release : Official Journal of the Controlled Release Society

|August 22, 2012

Summary

Nanotechnology offers advanced cancer detection and treatment by leveraging nanomaterials for targeted therapy and imaging. Overcoming biological barriers and demonstrating superior efficacy are key challenges for clinical translation of these promising nanomedicines.

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Last Updated: May 19, 2026

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Area of Science:

Oncology
Nanomedicine
Biomedical Engineering

Background:

Nanotechnology advances understanding of nanomaterial-biological interactions.
Multifunctional nanocomposites enable simultaneous cancer imaging and therapy (theranostics).
Unique nanoscale properties offer high selectivity and efficiency in cancer cell detection and destruction.

Purpose of the Study:

To explore the potential of nanotechnology in oncology.
To highlight the role of nanodiagnostics and nanotherapeutics.
To discuss challenges and opportunities in clinical translation.

Main Methods:

Harnessing unique physicochemical properties of nanomaterials.
Developing multifunctional nanocomposites for theranostics.
Investigating nanomaterial interactions with biological systems.

Main Results:

Nanoparticles offer high selectivity and efficiency in detecting and destroying cancer cells.
Image guidance plays a crucial role in nanoparticle-mediated theranostics.
Overcoming biological barriers is critical for clinical translation.

Conclusions:

Nanotechnology holds significant promise for advancing cancer care through improved diagnostics and targeted therapies.
Clinical translation requires addressing biological barriers and demonstrating superior therapeutic efficacy.
Image-guided nanoparticle delivery enhances safety and effectiveness of cancer treatments.