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[Proteolysis of the extracellular matrix in periodontal disease]
1Laboratoire de Biochimie, UFR d'Odontologie, Université René Descartes Paris V, Montrouge, France.
Pathologie-Biologie
|December 1, 1990
Abstract:
Maintenance of teeth in the alveolar ridges requires integrity of the tooth-gingiva attachment. The strength of this connection is due in part to the presence of collagen and fibronectin. The purpose of this study was to investigate factors capable of altering these two components. In both gingival explant culture extracts and fractions from bacteria associated with periodontal disease, enzyme activities against type I collagen and fibronectin were found.