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Related Concept Videos

Extracorporeal Removal of Drugs: Hemoperfusion and Hemofiltration01:25

Extracorporeal Removal of Drugs: Hemoperfusion and Hemofiltration

Hemoperfusion and hemofiltration are critical techniques in medical treatments to eliminate accumulated drugs, metabolites, and electrolytes from the bloodstream. These methods are particularly vital in cases of accidental poisoning and drug overdose.Hemoperfusion involves passing blood through an adsorbent material to remove unwanted substances. The main adsorbents used in hemoperfusion include activated charcoal and Amberlite resins. Activated charcoal can adsorb both polar and nonpolar...
Extracorporeal Removal of Drugs: Peritoneal Dialysis and Hemodialysis01:30

Extracorporeal Removal of Drugs: Peritoneal Dialysis and Hemodialysis

Patients with end-stage renal disease (ESRD) or those experiencing drug overdose often require extracorporeal methods to eliminate accumulated drugs and metabolites. Hemoperfusion, hemofiltration, and dialysis are the primary techniques to rapidly remove harmful substances without disrupting the patient's fluid and electrolyte balance. For those with compromised renal function, dosage adjustments of concurrent medications may be necessary during extracorporeal drug removal.Dialysis is a process...
Oxygen Delivering System II: Venturi Mask and Transtracheal Oxygen01:16

Oxygen Delivering System II: Venturi Mask and Transtracheal Oxygen

Oxygen therapy is a pivotal aspect of medical care, particularly for patients with respiratory ailments. Two prominent oxygen-delivering systems include the Venturi mask and the transtracheal oxygen catheter.
Venturi Mask
The Venturi mask, named after the Venturi effect, is designed to deliver precise oxygen concentrations. It consists of a large tube with an oxygen inlet that narrows down, causing a pressure drop that pulls air in through adjustable side ports. The mask is a lightweight,...
Extracorporeal Removal of Drugs: Continuous Renal Replacement Therapy01:26

Extracorporeal Removal of Drugs: Continuous Renal Replacement Therapy

Continuous Renal Replacement Therapy (CRRT) is an essential intervention for patients experiencing severe kidney dysfunction. This therapy offers a continuous mechanism for removing fluids and toxins from the bloodstream, leveraging the patient’s blood pressure to facilitate filtration through a specialized filter. This method contrasts with intermittent dialysis, providing a gentler and more consistent removal of waste products and excess fluid, which is particularly beneficial in critically...
Acute Respiratory Failure-II01:21

Acute Respiratory Failure-II

Type I Respiratory Failure, or hypoxemic respiratory failure, occurs when the partial pressure of oxygen (PaO2) in arterial blood falls below 60 mmHg while breathing room air without a corresponding increase in arterial carbon dioxide levels (PaCO2). This condition highlights a significant impairment in the lungs' capacity to oxygenate the blood.
The underlying physiological abnormalities that contribute to hypoxemic respiratory failure include:
Oxygen Delivering System III: Tracheostomy and T-piece01:23

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Oxygen delivery is critical in clinical care, especially for patients with respiratory disorders or those undergoing surgical procedures. Various systems, such as tracheostomy and the T-piece, deliver oxygen to the lungs, ensuring adequate arterial oxygenation.
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Related Experiment Video

Updated: May 19, 2026

Point-of-Care Ultrasound for Peripheral Veno-Arterial Extracorporeal Membrane Oxygenation Without Left Ventricular Venting
03:40

Point-of-Care Ultrasound for Peripheral Veno-Arterial Extracorporeal Membrane Oxygenation Without Left Ventricular Venting

Published on: January 17, 2025

[Extracorporeal lung support].

M Hecker1, D Bandorski, A Hecker

  • 1Medizinische Klinik II (Pneumologie/internistische Intensivmedizin), Universitätsklinikum Gießen und Marburg, Standort Gießen, Klinikstraße 33, 35392, Gießen, Deutschland. matthias.hecker@innere.med.uni-giessen.de

Medizinische Klinik, Intensivmedizin Und Notfallmedizin
|August 22, 2012
PubMed
Summary
This summary is machine-generated.

Extracorporeal membrane oxygenation (ECMO) is a life-saving lung support technique that has advanced significantly, offering a promising option for acute respiratory distress syndrome (ARDS) therapy in specialized centers. Further research is needed for newer pumpless devices.

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Establishment of a Novel Ex Vivo Lung Perfusion System for Rat Lungs After Circulatory Death
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Establishment of a Novel Ex Vivo Lung Perfusion System for Rat Lungs After Circulatory Death

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Last Updated: May 19, 2026

Point-of-Care Ultrasound for Peripheral Veno-Arterial Extracorporeal Membrane Oxygenation Without Left Ventricular Venting
03:40

Point-of-Care Ultrasound for Peripheral Veno-Arterial Extracorporeal Membrane Oxygenation Without Left Ventricular Venting

Published on: January 17, 2025

Establishment of a Novel Ex Vivo Lung Perfusion System for Rat Lungs After Circulatory Death
09:14

Establishment of a Novel Ex Vivo Lung Perfusion System for Rat Lungs After Circulatory Death

Published on: October 18, 2024

Area of Science:

  • Cardiovascular and Respiratory System Physiology
  • Medical Technology and Engineering

Background:

  • Extracorporeal lung support techniques, including extracorporeal membrane oxygenation (ECMO), have been available for decades in specialized centers.
  • Historically, ECMO application was linked to severe complications, but recent technical advancements have improved safety and accessibility.
  • Positive study data now support ECMO as a viable therapy for acute respiratory distress syndrome (ARDS).

Purpose of the Study:

  • To review the advancements and current status of extracorporeal lung support, particularly ECMO.
  • To evaluate ECMO's role in managing acute respiratory distress syndrome (ARDS).
  • To explore the potential of newer developments like pumpless extracorporeal lung support devices.

Main Methods:

  • Review of existing literature and study data on ECMO and related technologies.
  • Analysis of technical progress in ECMO systems.
  • Assessment of clinical outcomes and application in ARDS therapy.

Main Results:

  • Significant technical progress has led to safer ECMO systems, increasing its adoption.
  • ECMO is recognized as a promising therapeutic option for ARDS in specialized centers.
  • Pumpless extracorporeal lung support devices show potential but lack prospective efficacy data.

Conclusions:

  • ECMO has evolved into a safer and more widely distributed technique for lung function substitution.
  • ECMO is a valuable tool for ARDS management in expert centers.
  • Further prospective studies are required to validate the efficacy of novel pumpless extracorporeal lung support systems for intensive care medicine.