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Acute Pyelonephritis I: Introduction01:27

Acute Pyelonephritis I: Introduction

Pyelonephritis is a bacterial infection that primarily affects the renal parenchyma and collecting system, including the renal pelvis, tubules, and interstitial tissue of one or both kidneys. It can be classified as either acute—a sudden, severe infection—or chronic, which refers to long-term or recurrent kidney infections.The primary cause of acute pyelonephritis (APN) is bacterial infection, with Escherichia coli accounting for approximately 70-80% of cases. Other bacteria, such as Proteus,...
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Subcutaneous Infection of Methicillin Resistant Staphylococcus Aureus (MRSA)
12:18

Subcutaneous Infection of Methicillin Resistant Staphylococcus Aureus (MRSA)

Published on: February 9, 2011

Primary neonatal MRSA pyonephrosis.

Ramnik Patel1, Ngozi Nwokoma, George K Ninan

  • 1The Department of Paediatric Urology, Children's Hospital, University Hospitals of Leicester NHS Trust, Leicester Royal Infirmary, Infirmary Square, Infirmary Road, Leicester, LE1 5WW, UK.

International Urology and Nephrology
|August 22, 2012
PubMed
Summary
This summary is machine-generated.

This case report details the first instance of Methicillin-resistant Staphylococcus aureus (MRSA) pyonephrosis in a neonate. Prompt surgical intervention was crucial for treating this rare and severe condition.

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A Neonatal Imaging Model of Gram-Negative Bacterial Sepsis
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A Neonatal Imaging Model of Gram-Negative Bacterial Sepsis

Published on: August 12, 2020

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Last Updated: May 19, 2026

Subcutaneous Infection of Methicillin Resistant Staphylococcus Aureus (MRSA)
12:18

Subcutaneous Infection of Methicillin Resistant Staphylococcus Aureus (MRSA)

Published on: February 9, 2011

A Neonatal Imaging Model of Gram-Negative Bacterial Sepsis
08:46

A Neonatal Imaging Model of Gram-Negative Bacterial Sepsis

Published on: August 12, 2020

Area of Science:

  • Neonatal medicine
  • Infectious diseases
  • Pediatric surgery

Background:

  • Pyonephrosis, a severe kidney infection, is rare in neonates.
  • Previous reports include candidal and staphylococcal causes.

Observation:

  • A neonate presented with a rapidly progressing primary MRSA pyonephrosis and septic shock.
  • Investigations revealed a refluxing and obstructing left megaureter.

Findings:

  • This is the first reported case of Methicillin-resistant Staphylococcus aureus (MRSA) causing pyonephrosis in a neonate.
  • The neonate had a life-threatening infection complicated by a structural urinary tract abnormality.

Implications:

  • Highlights the potential for MRSA to cause severe neonatal infections.
  • Emphasizes the need for timely diagnosis and surgical correction of urinary tract abnormalities in neonatal sepsis.
  • Underscores the importance of considering unusual pathogens in neonatal infections.