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Related Experiment Video

Updated: May 19, 2026

In vivo Structural Assessments of Ocular Disease in Rodent Models using Optical Coherence Tomography
07:44

In vivo Structural Assessments of Ocular Disease in Rodent Models using Optical Coherence Tomography

Published on: July 24, 2020

Torpedo maculopathy: a morphofunctional evaluation.

Elisabetta Pilotto1, Maria Elisabetta Zannin, Enrica Convento

  • 1Department of Ophthalmology, University of Padova, via Giustiniani 2, Padua, Italy. elisabetta.pilotto@unipd.it

International Ophthalmology
|August 22, 2012
PubMed
Summary
This summary is machine-generated.

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This study details torpedo maculopathy in a child, revealing a congenital retinal pigment epithelium defect. Advanced imaging showed no neuroretinal changes, suggesting early detection is key.

Area of Science:

  • Ophthalmology
  • Retinal Imaging
  • Congenital Ocular Disorders

Background:

  • Torpedo maculopathy is a rare, unilateral temporal macular lesion.
  • Understanding its characteristics requires advanced imaging techniques.

Observation:

  • A 4-year-old female with torpedo maculopathy underwent spectral-domain optical coherence tomography (SD-OCT), short-wavelength fundus autofluorescence (SW-FAF), and near-infrared fundus autofluorescence (NIR-FAF).
  • Microperimetry was used to assess retinal sensitivity.

Findings:

  • SD-OCT revealed a thin retinal pigment epithelium and increased choroidal signal transmission without neuroretinal changes.
  • SW-FAF showed normal fluorescence with a hyperfluorescent tail, while NIR-FAF demonstrated hypofluorescence.
  • Microperimetry indicated reduced sensitivity at the lesion margins but normal sensitivity over the lesion.

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Last Updated: May 19, 2026

In vivo Structural Assessments of Ocular Disease in Rodent Models using Optical Coherence Tomography
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In vivo Structural Assessments of Ocular Disease in Rodent Models using Optical Coherence Tomography

Published on: July 24, 2020

Implantation and Evaluation of Melanoma in the Murine Choroid via Optical Coherence Tomography
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Implantation and Evaluation of Melanoma in the Murine Choroid via Optical Coherence Tomography

Published on: December 2, 2022

Implications:

  • The findings support a congenital defect of the retinal pigment epithelium.
  • The absence of functional and neuroretinal changes may be attributed to the early detection of the lesion.
  • This case highlights the utility of multimodal imaging in characterizing rare macular conditions.