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Published on: July 18, 2025
Minimized perfusion circuits: an alternative in the surgical treatment of Jehovah's Witnesses
A El-Essawi1, I Breitenbach, K Ali
1Klinikum Braunschweig, Department of Thoracic and Cardiovascular Surgery, Braunschweig, Germany. aelessawi@aol.com
Insights
Minimized perfusion circuits (MPC) enable bloodless cardiac surgery for Jehovah's Witnesses, achieving excellent outcomes. This study highlights MPCs as a safe and effective option for this patient population.
Area of Science:
- Cardiovascular Surgery
- Transfusion Medicine
- Patient Safety
Background:
- Jehovah's Witnesses require bloodless cardiac surgery, posing a challenge to standard surgical practices.
- Minimally invasive techniques, including minimized perfusion circuits (MPC), have emerged to address this need.
- Optimizing care for Jehovah's Witnesses involves balancing surgical outcomes with transfusion avoidance.
Purpose of the Study:
- To evaluate the safety and efficacy of minimized perfusion circuits (MPC) in cardiac surgery for Jehovah's Witnesses.
- To assess the impact of MPCs on patient outcomes, including mortality, morbidity, and length of stay.
- To demonstrate the role of MPCs in enhancing the quality of care for patients refusing blood transfusions.
Main Methods:
- Retrospective analysis of 29 Jehovah's Witnesses undergoing cardiac surgery with MPCs since 2005.
- Utilization of the ROCsafe (reservoir optional circuit) MPC in 27 patients for enhanced safety.
- Data collection on perioperative outcomes, complications, and transfusion avoidance.
Main Results:
- No in-hospital or 30-day postoperative mortality observed.
- Low rates of complications including myocardial infarction, stroke, and delirium.
- Mean ICU stay of 1.6 days and intubation time of 11.3 hours.
- Mean postoperative hospital stay of 9.9 days with minimal hemoglobin decrease.
Conclusions:
- Minimized perfusion circuits (MPCs) are effective in facilitating bloodless cardiac surgery for Jehovah's Witnesses.
- MPCs contribute significantly to optimizing patient care and safety in this specific population.
- These findings encourage the wider adoption of MPCs for similar surgical cases.
Objectives:
Jehovah's Witnesses present a challenge to cardiac surgeons, as quality of care is not only defined by mortality and morbidity, but also by the avoidance of blood transfusions. Over the last years, minimized perfusion circuits (MPC) have contributed substantially to the achievement of this goal in our clinic. Presented is a retrospective analysis of our experience.
Methods:
Twenty-nine Jehovah's Witnesses, aged 69 ± 10 years, have undergone cardiac surgery with a MPC in our institution since 2005. The ROCsafe (reservoir optional circuit) MPC was used in most of these patients (n=27) as it offers the unique possibility of a speedy integration of a reservoir in the event of a major air leak, thereby, negligating any safety concerns.
Results:
There was no in-hospital or 30-day postoperative mortality. Mean ICU stay was 1.6 ± 2 days with a mean intubation time of 11.3 ± 9.1 hrs. Postoperative complications included one myocardial infarction with accompanying low cardiac output, one stroke, one transient delirium, one idiopathic thrombocytopenia and three re-operations (one sternal infection, one postoperative bleeding and one delayed tamponade). The mean postoperative hospital stay was 9.9 ± 2.3 days. Mean decrease in hemoglobin was 2.1 ± 1.3 g/dl during cardiopulmonary bypass and 3.4 ±1.4 g/dl at discharge. The lowest postoperative hemoglobin level was 9.3 ±1.8 (Range 6-12.9).
Conclusions:
These encouraging results emphasize the role MPCs can play in optimizing the quality of patient care. We hope that this report can serve as a stimulus for similar experiences.

