Related Experiment Video
Updated: May 19, 2026
07:15
Anaerobic Growth and Maintenance of Mammalian Cell Lines
Published on: July 21, 2018
A long-awaited discovery: hypoxia prevents mouse cells from undergoing spontaneous p53-dependent transformation
Cytotherapy
|August 23, 2012
Abstract:
A recent publication by Phinney and his associates (1) has presented a discovery for which the field of cell biology has been waiting for more than half a century: a protocol that makes it possible to expand mouse cells in culture without the cells spontaneously transforming. Amazing though it seems, the secret is simply to grow the cells under hypoxic conditions.
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