Related Experiment Video
Updated: May 19, 2026

Isolation of Leukocytes from Human Breast Milk for Use in an Antibody-dependent Cellular Phagocytosis Assay of HIV Targets
Published on: September 6, 2019
Maternal antiretroviral prophylaxis and breastfeeding
Catia Marzolini1, Glenda E Gray
1Division of Infectious Diseases and Hospital Epidemiology, University Hospital Basel, Switzerland. MarzoliniC@uhbs.ch
Abstract:
The prevention of mother-to-child transmission of HIV-1 during breastfeeding is a major concern in resource-poor settings where alternatives to breast milk may be unaffordable, unsafe and limited by social stigma. The use of triple-drug antiretroviral regimens initiated during pregnancy and continued throughout breastfeeding is being studied as a means to prevent transmission by reducing HIV-1 viral load in the maternal serum and breast milk. Studies characterizing the exposure of antiretroviral agents in breast milk and in the breastfed infant are important to understand the dynamics of HIV-1 replication in breast milk and to establish the safety profiles of antiretroviral drugs.
Related Concept Videos
Pharmacokinetics in Pediatric Patients: Drug Excretion
Development of the Oral Microbiota
Retrovirus Life Cycles
Development of Immunocompetence
The initial cells that migrate from the fetal thymus settle within the skin and epithelial tissues lining the mouth, digestive tract, and in females, the uterus and vagina. These cells, including skin-based dendritic cells, serve as antigen-presenting cells, playing a key role in T cell activation.
Subsequent T...
Development of Human Microbiota
Teratogenicity

