Related Experiment Video
Updated: May 19, 2026

Generating Genetically Modified Plasmodium berghei Sporozoites
Published on: May 5, 2023
Overview of plant-made vaccine antigens against malaria
Marina Clemente1, Mariana G Corigliano
1Laboratorio de Biotecnología Vegetal, Instituto Investigaciones Biotecnológicas-Instituto Tecnológico Chascomús, Camino de Circunvalación km 8.2, 7130 Buenos Aires, Argentina. mclemente@intech.gov.ar
Abstract:
This paper is an overview of vaccine antigens against malaria produced in plants. Plant-based expression systems represent an interesting production platform due to their reduced manufacturing costs and high scalability. At present, different Plasmodium antigens and expression strategies have been optimized in plants. Furthermore, malaria antigens are one of the few examples of eukaryotic proteins with vaccine value expressed in plants, making plant-derived malaria antigens an interesting model to analyze. Up to now, malaria antigen expression in plants has allowed the complete synthesis of these vaccine antigens, which have been able to induce an active immune response in mice. Therefore, plant production platforms offer wonderful prospects for improving the access to malaria vaccines.
Related Concept Videos
Overview of Protists
Vaccines
Vaccinations
Diversity of Protists II
Symbiosis
Vaccine Production

