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Hepatitis B and C Infections in Hamadan Province during 2004-2009

Jalal Poorolajal1, Mohammad Mirzaei, Seyyed Jalal Bathaei

  • 1a Department of Epidemiology & Biostatistics and Research Center for Health Sciences, School of Public Health, Hamadan University of Medical Sciences, Hamadan, Iran.

Journal of Research in Health Sciences
|August 23, 2012
PubMed

Insights

Hepatitis B virus (HBV) infection incidence declined significantly in Iran from 2004-2009, likely due to vaccination. Hepatitis C virus (HCV) infection rates fluctuated, warranting attention from health policymakers.

Area of Science:

  • Hepatology
  • Infectious Diseases
  • Public Health Epidemiology

Background:

  • Hepatitis B virus (HBV) and hepatitis C virus (HCV) represent significant global health challenges.
  • This study addresses the incidence rates of HBV and HCV infections in Hamadan Province, Iran, over a six-year period.

Purpose of the Study:

  • To investigate the incidence trends of HBV and HCV infections in Hamadan Province, Iran, from 2004 to 2009.
  • To analyze age-specific incidence rates and temporal changes in HBV and HCV infections.

Main Methods:

  • A retrospective cohort study utilizing hepatitis registry data.
  • Inclusion of 1257 HBV-infected and 705 HCV-infected individuals.
  • Detection of HBV via HBsAg presence and HCV via Anti-HCV antibodies.

Main Results:

  • HBV incidence per 100,000 population decreased from 19.60 in 2004 to 7.70 in 2009 (P<0.001).
  • HCV incidence per 100,000 population showed fluctuations, decreasing from 6.73 in 2004 to 5.17 in 2009 (P<0.001).
  • The rate ratio for HBV trend was 0.85 (95% CI: 0.82, 0.88), indicating a significant decrease, while HCV's was 0.94 (95% CI: 0.90, 0.99).

Conclusions:

  • The decline in HBV incidence is potentially attributed to widespread national immunization programs for newborns and adolescents.
  • The fluctuating and temporarily increasing incidence of HCV infection highlights a critical public health concern requiring focused attention from policymakers.
  • Continued monitoring and targeted interventions are crucial for managing hepatitis infections in the region.
Abstract

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