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Prophylaxis of infection-induced kidney stone formation
1Policlinic of Medicine, University of Berne, Switzerland.
Urological Research
|January 1, 1990
Abstract:
Lowering supersaturation with respect to struvite and carbonate apatite is the most important prophylactic measure in patients with infection-induced kidney stone disease. This is best achieved by combining culture-specific antibiotics with urinary acidification. Urinary infection with non-urease-producing Escherichia coli, probably promoting struvite particle formation, must be eradicated. Possible measures for improving urothelial anti-adherence properties or reducing bacterial adherence are discussed.