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Managing gastroesophageal reflux disease in children: The role of endoscopy
Helena As Goldani1, Daltro La Nunes, Cristina T Ferreira
1Helena AS Goldani, Daltro LA Nunes, Cristina T Ferreira, Department of Pediatrics and Gastroenterology Unit, Hospital de Clinicas de Porto Alegre, Faculdade de Medicina da Universidade Federal do Rio Grande do Sul, 90035-903 Porto Alegre-RS, Brazil.
Insights
Pediatric gastroesophageal reflux disease (GERD) management requires special attention to growth stages. Esophago-gastroduodenoscopy (EGD) with biopsy is crucial for diagnosing GERD in children and ruling out other conditions like eosinophilic esophagitis.
Area of Science:
- Pediatric Gastroenterology
- Gastrointestinal Endoscopy
Background:
- Gastroesophageal reflux disease (GERD) is increasingly prevalent in children, yet management differs from adults due to developmental stages.
- Current GERD knowledge primarily stems from adult studies, necessitating a focus on pediatric-specific considerations.
Purpose of the Study:
- To highlight the specialized role of esophago-gastroduodenoscopy (EGD) with biopsy in diagnosing and managing pediatric GERD.
- To emphasize the importance of considering developmental stages in pediatric GERD management.
Main Methods:
- Review of current literature on pediatric GERD and the diagnostic utility of EGD.
- Analysis of EGD findings in children, including tissue damage assessment and differential diagnosis.
Main Results:
- EGD with biopsy is essential for assessing GERD-related tissue damage in children, despite the lack of a gold standard diagnostic test.
- EGD plays a vital role in differentiating GERD from other causes of esophagitis, such as eosinophilic esophagitis, in pediatric patients.
Conclusions:
- Pediatric GERD management requires a tailored approach, acknowledging distinct features from adult GERD.
- Esophago-gastroduodenoscopy (EGD) with biopsy is a key diagnostic tool in pediatric GERD, aiding in severity assessment and differential diagnosis.
Abstract:
Gastroesophageal reflux disease (GERD) is a growing problem in the pediatric population and recent advances in diagnostics and therapeutics have improved their management, particularly the use of esophago-gastroduodenoscopy (EGD). Most of the current knowledge is derived from studies in adults; however there are distinct features between infant onset and adult onset GERD. Children are not just little adults and attention must be given to the stages of growth and development and how these stages impact the disease management. Although there is a lack of a gold standard test to diagnose GERD in children, EGD with biopsy is essential to assess the type and severity of tissue damage. To date, the role of endoscopy in adults and children has been to assess the extent of esophagitis and detect metaplastic changes complicating GERD; however the current knowledge points another role for the EGD with biopsy that is to rule out other potential causes of esophagitis in patients with GERD symptoms such as eosinophilic esophagitis. This review highlights special considerations about the role of EGD in the management of children with GERD.
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