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Establishment of a Simple and Effective Rat Model for Intraoperative Parathyroid Gland Imaging

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Published on: August 17, 2022

Mediastinal parathyroid adenoma: a case report.

C Di Cosimo¹, A Metere, C Chiesa

¹Department of Surgical Sciences, Sapienza University, Rome, Italy. Carla.dicosimo@gmail.com

European Review for Medical and Pharmacological Sciences

|August 24, 2012

Summary

Ectopic parathyroid adenomas are rare and challenging to diagnose. This case highlights a mediastinal parathyroid adenoma missed by initial imaging, requiring advanced CT for localization and surgical removal.

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Area of Science:

Endocrinology
Surgical Pathology
Diagnostic Imaging

Background:

Ectopic parathyroid adenomas are uncommon and pose diagnostic difficulties.
Symptomatic hypercalcemia can be caused by these rare tumors.

Observation:

A 61-year-old male presented with hypercalcemia due to an ectopic parathyroid adenoma.
Initial ultrasonography and scintigraphy suggested thyroid nodules, but failed to localize the mediastinal adenoma.
Post-thyroid surgery, persistent hypercalcemia indicated an undiagnosed ectopic adenoma.

Findings:

A CT scan revealed a 27 x 22 mm mass in the upper anterior mediastinum.
Histopathology confirmed the mass as a parathyroid adenoma.
Successful removal was achieved via a laterocervical approach.

Implications:

This case underscores the importance of considering ectopic parathyroid adenomas in cases of persistent hypercalcemia.
Advanced imaging like CT is crucial for localizing these challenging lesions.
Multidisciplinary diagnostic and surgical approaches are vital for successful management.