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Evaluating measles vaccines: can we assess cellular immunity?

Rory D de Vries1, Rik L de Swart

  • 1Department of Virology, Erasmus MC, PO Box 2040, 3000 CA, Rotterdam, The Netherlands.

Expert Review of Vaccines
|August 24, 2012
PubMed

Insights

Global measles eradication efforts face challenges. This study found limited correlation between humoral and cellular immune responses after measles vaccination, questioning their combined use as protection indicators.

Area of Science:

  • Immunology
  • Vaccinology
  • Public Health

Background:

  • Measles is a significant cause of childhood mortality globally.
  • Live-attenuated measles vaccines have limitations, prompting research into new vaccines and administration routes.
  • Understanding immune responses to vaccination is crucial for disease control and eradication.

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