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Updated: May 19, 2026

Effect of Artificial Tear Formulations on the Metabolic Activity of Human Corneal Epithelial Cells after Exposure to Desiccation
Published on: May 2, 2020
Emollients are more than sensory ingredients: the case of isostearyl isostearate
J C Dederen1, B Chavan, A V Rawlings
1Croda Consumer Care Europe, Dorpsstraat 144a, B-3078, Meerbeek, Belgium. chris.dederen@croda.com
Abstract:
In order to understand the skin benefits of emollient oil ingredients in topical skin moisturizers, one single highly popular in vivo method (corneometry), even when executed to perfection, does not suffice. A systematical exploration using a combination of bioengineering techniques shows how a previously unaccounted for mechanism of moisturization by internal occlusion was discovered. As a result, Isostearyl Isostearate turns out to be a highly functional moisturizer when several methodologies are used.
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