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Updated: May 19, 2026
14:14
Standardized Technique of Aortic Valve Re-implantation for Valve-sparing Aortic Root Replacement
Published on: December 11, 2017
Clinical outcomes of aortic root replacement after previous aortic root replacement
Luis Garrido-Olivares1, Manjula Maganti, Susan Armstrong
1Division of Cardiovascular Surgery, Peter Munk Cardiac Center, Toronto General Hospital, Toronto, Ontario, Canada.
The Journal of Thoracic and Cardiovascular Surgery
|August 24, 2012
Summary
Reoperative aortic root replacement has low operative mortality but suboptimal long-term survival. Increasing age and prosthetic valve endocarditis negatively impact outcomes in patients undergoing repeat aortic root surgery.
Area of Science:
- Cardiovascular Surgery
- Thoracic Surgery
- Aortic Surgery
Background:
- Reoperative aortic root replacement is a complex procedure following initial aortic root surgery.
- Indications for reoperation often include bioprosthetic valve failure or prosthetic valve endocarditis.
Purpose of the Study:
- To evaluate the short- and long-term clinical outcomes of patients undergoing reoperative aortic root replacement.
- To identify risk factors associated with mortality after reoperative aortic root replacement.
Main Methods:
- A retrospective analysis of 84 patients who underwent reoperative aortic root replacement between 1985 and 2011.
- Cox proportional hazard regression modeling was used to determine independent risk factors for mortality.
Main Results:
- The study reported a 6% operative mortality rate and significant perioperative morbidity.
- Long-term survival rates at 5, 10, and 12 years were 82.5%, 72.5%, and 65.0%, respectively.
- Increasing age and prosthetic valve endocarditis were identified as independent risk factors for mortality.
Conclusions:
- Reoperative aortic root replacement is feasible with acceptable operative risk.
- Long-term survival remains a concern, highlighting the need for careful patient selection and management.
- Prosthetic valve endocarditis and advanced age are critical factors influencing survival post-reoperation.
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