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Transient tonic upgaze deviation: a neuro-ophthalmological complication of acute cerebellitis
Jeremy Lankford1, Ian J Butler
1Division of Child and Adolescent Neurology, Department of Pediatrics, The University of Texas Health Science Center, Houston, TX 77030, USA.
Insights
Acute cerebellitis, an inflammatory brain condition, can cause cerebellar dysfunction and eye movement issues in children. This case study shows a child
Area of Science:
- Pediatric Neurology
- Neuroinflammation
Background:
- Acute cerebellitis is an inflammatory syndrome affecting the cerebellum in children.
- Symptoms include cerebellar dysfunction, and potential complications like cerebellar tonsillar herniation and hydrocephalus.
Abstract:
Acute cerebellitis in children is an inflammatory syndrome with symptoms of cerebellar dysfunction. We describe a 3-year-old boy with acute cerebellitis who had cerebellar tonsillar herniation, hydrocephalus, and transient tonic bilateral upward gaze deviation. Although no etiology for his acute cerebellitis was determined, he fully recovered with high-dose corticosteroids, intravenous immunoglobulin, and antimicrobial therapy. We propose that there was tonic irritation of the upward gaze generator cells in the superior colliculus as an explanation for temporary disturbance of his ocular gaze.
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