Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Classification and Mechanical Properties of Synthetic Polymers01:28

Classification and Mechanical Properties of Synthetic Polymers

Synthetic polymers are classified as elastomers, fibers, or plastics based on their crystallinity. Crystallinity, the degree of long-range order in the solid state, influences the mechanical properties (stretching or contracting) of elastomers. Elastomers are flexible polymers that can expand or contract easily upon the application of an external force. They have numerous crosslinks that pull them back into their original shape when stress is removed. Silicones, for instance, are highly elastic...
Members Made of Elastoplastic Material01:19

Members Made of Elastoplastic Material

The behavior of elastoplastic materials under bending stresses, particularly in structural members with rectangular cross-sections, is crucial for predicting material responses and understanding failure modes. Initially, when a bending moment is applied, the stress distribution across the section follows Hooke's Law and is linear and elastic. This distribution means the stress increases from the neutral axis to the maximum at the outer fibers, up to the elastic limit.
As the bending moment...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Outpatient Parenteral Antimicrobial Therapy in a Tertiary Hospital in France: A Description of Service Models and Costs.

Antibiotics (Basel, Switzerland)·2025
Same author

Sunitinib as Second-Line Treatment in Advanced Intrahepatic Cholangiocarcinoma: Results From the SUN-CK GERCOR Phase II Trial.

Liver international : official journal of the International Association for the Study of the Liver·2025
Same author

Outpatient parenteral antibiotic therapy with elastomeric pumps, what is the flowrate accuracy?

The journal of vascular access·2025
Same author

The Infusion of Piperacillin/Tazobactam with an Elastomeric Device: A Combined 24-H Stability Study and Drug Solution Flow Rate Analysis.

Pharmaceuticals (Basel, Switzerland)·2024
Same author

Intensive chemotherapy followed by autologous stem cell transplantation in primary central nervous system lymphomas (PCNSLs). Therapeutic outcomes in real life-experience of the French Network.

Bone marrow transplantation·2022
Same author

Long-term outcomes of lentiviral gene therapy for the β-hemoglobinopathies: the HGB-205 trial.

Nature medicine·2022

Related Experiment Video

Updated: May 19, 2026

Fabrication Process of Silicone-based Dielectric Elastomer Actuators
10:32

Fabrication Process of Silicone-based Dielectric Elastomer Actuators

Published on: February 1, 2016

Mechanical performances of elastomers used in diffusers.

Gérard Guiffant1, Jean-Jacques Durussel, Patrice Flaud

  • 1University Paris Diderot, Paris, France.

Medical Devices (Auckland, N.Z.)
|August 24, 2012
PubMed
Summary

Elastomeric diffusers (EDs) used in home care show varying mechanical properties. Silicone and polyisoprene elastomers impact infusion flow rate consistency, raising concerns for intravenous therapies.

Keywords:
drug administration rateelastomeric diffusersinfusion devicesinfusion flowperfusion

More Related Videos

Synthesis of Programmable Main-chain Liquid-crystalline Elastomers Using a Two-stage Thiol-acrylate Reaction
11:17

Synthesis of Programmable Main-chain Liquid-crystalline Elastomers Using a Two-stage Thiol-acrylate Reaction

Published on: January 19, 2016

Applying Permanent, Robust Stenciled Patterns of Fine Particles to Elastomeric Surfaces
07:12

Applying Permanent, Robust Stenciled Patterns of Fine Particles to Elastomeric Surfaces

Published on: July 8, 2025

Related Experiment Videos

Last Updated: May 19, 2026

Fabrication Process of Silicone-based Dielectric Elastomer Actuators
10:32

Fabrication Process of Silicone-based Dielectric Elastomer Actuators

Published on: February 1, 2016

Synthesis of Programmable Main-chain Liquid-crystalline Elastomers Using a Two-stage Thiol-acrylate Reaction
11:17

Synthesis of Programmable Main-chain Liquid-crystalline Elastomers Using a Two-stage Thiol-acrylate Reaction

Published on: January 19, 2016

Applying Permanent, Robust Stenciled Patterns of Fine Particles to Elastomeric Surfaces
07:12

Applying Permanent, Robust Stenciled Patterns of Fine Particles to Elastomeric Surfaces

Published on: July 8, 2025

Area of Science:

  • Materials Science
  • Biomedical Engineering
  • Pharmacology

Background:

  • Elastomeric diffusers (EDs) are increasingly utilized in home healthcare settings.
  • These devices feature pre-set drug reservoir fill volumes and flow rates.
  • Infusate flow is driven by the pressure exerted by the elastomer reservoir walls.

Purpose of the Study:

  • To quantify the mechanical performance of silicone and polyisoprene elastomers in EDs.
  • To assess the impact of elastomer mechanical properties on infusion flow rate consistency.
  • To evaluate ED performance under standardized experimental and recommended use conditions.

Main Methods:

  • Standardized experimental conditions were employed.
  • Recommended conditions of use were followed.
  • Mechanical performances of silicone and polyisoprene elastomers were quantified.

Main Results:

  • Significant differences in mechanical performances were observed between silicone and polyisoprene elastomers.
  • These mechanical variations directly impact the consistency of the infusion flow rate.
  • The findings highlight potential issues with EDs for specific intravenous therapies.

Conclusions:

  • The mechanical properties of elastomers used in EDs are not uniform.
  • Inconsistent mechanical performance can compromise the reliability of infusion delivery.
  • Careful consideration of elastomer type is necessary for specific intravenous therapy applications using EDs.