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Updated: May 19, 2026

Characterization of Sickling During Controlled Automated Deoxygenation with Oxygen Gradient Ektacytometry
Published on: November 5, 2019
[Sickle-cell anemia and pain]
1Département d'anesthésie-réanimation-douleur, Institut Curie, Paris. alicedesmouliere@hotmail.fr
Abstract:
Sickle-cell anaemia is the most widespread genetic disease in the world. It manifests itself differently depending on the individual, but approximately 20% of patients affected suffer from very frequent and severe vaso-occlusive crises. The red blood cells, deformed into a sickle shape, obliterate the small blood vessels, reducing the oxygen supply to the organs. It is the main reason that patients with sickle-cell anaemia seek medical care in hospital emergency departments. Morphine is the basic treatment.
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