[Liver transplant at the UMAE 25 IMSS Monterrey]

Area of Science:

• Hepatology and Transplant Surgery
• Clinical Outcomes Research

Context:

• Liver transplantation is a life-saving treatment for end-stage liver disease.
• Established in April 2003, the UMAE 25 Monterrey N.L. initiated a comprehensive Liver Transplantation Program.
• The program serves both pediatric and adult patient populations.

Purpose:

• To present the outcomes of the Liver Transplantation Program at UMAE 25 Monterrey N.L.
• To analyze patient demographics, indications for transplantation, complications, and survival rates.
• To evaluate the quality of life following liver transplantation.

Summary:

• A retrospective cohort study analyzed 51 liver transplantations in 49 patients (15 pediatric, 36 adult).
• Key indications included biliary atresia in children and hepatitis C cirrhosis in adults.
• Early complications involved acute renal failure, intermediate complications included acute cellular rejection, and late complications were cardiovascular diseases linked to metabolic conditions. Overall 1- and 5-year survival rates were 57.1% and 54.2%, respectively, with good quality of life observed within three years post-transplant.

Impact:

• Demonstrates the feasibility and initial outcomes of a developing liver transplant program serving diverse age groups.
• Highlights common complications and survival metrics crucial for refining transplant protocols.
• Provides evidence of improved quality of life post-transplantation, underscoring the program's success.