Related Experiment Videos

Labile hypertension: characteristics of a referred cohort

Matthew R Elliott1, Jose M Soto Soto, William E Haley

  • 1Mayo Clinic Florida, FL, USA.

Clinical and Experimental Hypertension (New York, N.Y. : 1993)
|August 25, 2012
PubMed

Insights

Labile high blood pressure (LHBP) shows age-related changes in blood pressure variability (BPV). Aging impacts systolic and diastolic BPV, widening pulse pressure and altering diurnal patterns.

Area of Science:

  • Cardiology
  • Hypertension Research
  • Geriatric Medicine

Background:

  • Labile high blood pressure (LHBP) is common in older adults.
  • Understanding blood pressure variability (BPV) is crucial for managing hypertension.
  • The influence of aging on BPV patterns requires further investigation.

Purpose of the Study:

  • To investigate the relationship between age, medications, and blood pressure variability (BPV) in patients with labile high blood pressure (LHBP).
  • To analyze the diurnal patterns and pulse pressure in relation to aging in LHBP subjects.

Main Methods:

  • Ambulatory blood pressure monitoring was used to collect data from 88 subjects with LHBP.
  • Blood pressure variability (BPV) was assessed and correlated with age, medication use, and nocturnal patterns.

Main Results:

  • BPV did not significantly differ between diurnal and nocturnal periods and was not influenced by antihypertensive medications.
  • Aging was associated with increased daytime systolic BPV and nighttime systolic BP.
  • Aging correlated with decreased diurnal diastolic BP, widened pulse pressure, and abnormal diurnal patterns.

Conclusions:

  • Aging significantly impacts blood pressure variability and diurnal patterns in individuals with LHBP.
  • Antihypertensive medications did not appear to influence BPV in this cohort.
  • Further research is necessary to stratify individual risks associated with LHBP and aging.

Related Concept Videos

Hypertension III: Clinical Manifestations and Diagnostic Studies01:30

Hypertension III: Clinical Manifestations and Diagnostic Studies

Hypertension is asymptomatic and also referred to as the "silent killer" until it progresses to a severe stage or causes target organ disease. Patients may experience symptoms stemming from the strain on blood vessels and tissues in various organs or the heart's increased workload.Physical exams might show no abnormalities other than high blood pressure. Signs of vascular damage, when present, correspond to the organs supplied by the affected vessels, leading to target organ damage. For...
Hypertension I: Introduction01:28

Hypertension I: Introduction

Hypertension is a widespread, long-term medical condition where blood pressure in the arteries remains elevated. It is characterized by systolic blood pressure readings of 130 mm Hg or above or diastolic blood pressure (DBP) readings of 80 mm Hg or higher. Unmanaged hypertension poses significant health risks, making the distinction between primary (or essential) hypertension and secondary hypertension crucial, as their management and implications vary.Primary HypertensionPrimary hypertension,...
Alterations in Blood Pressure01:30

Alterations in Blood Pressure

Alterations in blood pressure, such as hypertension (high blood pressure) and hypotension (low blood pressure), significantly affect human health. Understanding these conditions' classifications, causes, and symptoms is essential for effective management and treatment.
Hypertension (High blood pressure)
Hypertension occurs when blood pressure readings consistently exceed the normal range. It is diagnosed when systolic blood pressure (the top number, indicating pressure while the heart beats)...
Hypertension and Regulation of Blood Pressure01:18

Hypertension and Regulation of Blood Pressure

Hypertension, the most common cardiovascular disease, is diagnosed through repeated measurements of elevated blood pressure. Its risks, including damage to the kidney, heart, and brain, are directly proportional to blood pressure levels. Starting from 115/75 mm Hg, the risk of cardiovascular disease doubles with each increment of 20/10 mm Hg. The diagnosis relies on blood pressure measurements, not on patient symptoms, as hypertension is often asymptomatic until end-organ damage is imminent or...
Errors occurring during blood pressure monitoring01:25

Errors occurring during blood pressure monitoring

Blood pressure monitoring is a crucial clinical procedure in diagnosing and managing various cardiovascular conditions. Despite its significance, the accuracy of blood pressure measurements can be compromised by multiple factors, potentially leading to either falsely high or low readings. These inaccuracies are critical as they can significantly impact patient care. So, it is vital to understand these challenges deeply and adopt strategic approaches to minimize errors.
Several factors...
Measurement of Blood Pressure01:17

Measurement of Blood Pressure

Assessing blood pressure is a standard procedure executed in virtually all medical environments. The method utilized today was established over a hundred years ago by an innovative Russian doctor, Dr. Nikolai Korotkoff. The soft ticking noise, known as Korotkoff sounds, heard while taking blood pressure readings results from turbulent blood flow within the vessels. The apparatus required for this procedure includes a sphygmomanometer, a blood pressure cuff attached to a gauge, and a stethoscope.