Related Experiment Video
Updated: May 19, 2026

Halogenated Agent Delivery in Porcine Model of Acute Respiratory Distress Syndrome via an Intensive Care Unit Type Device
Published on: September 24, 2020
Work-related health effects in swine building workers after respiratory protection use
Jakob Hjort Bønløkke1, Marc Veillette, Anne Mériaux
1Department of Environmental and Occupational Health, Institute of Public Health, Aarhus University, Aarhus, Denmark. jb@mil.au.dk
Objective:
To compare inflammation and lung function in swine workers after periods with and without respiratory protection during work.
Methods:
Twenty-three workers were examined before and after two nonprotected work shifts. One shift was preceded by a period with diminished exposure by use of respirators. The other shift was preceded by an unprotected period of work.
Results:
Endotoxin concentrations were similarly high (24,636 and 28,775 endotoxin units/m(3)). A 3.1% cross-shift decline in forced vital capacity occurred after the period with respiratory protection (P = 0.01). Blood leukocytes increased more (P = 0.01) and bactericidal/permeability-increasing protein was reduced (P = 0.015) only after the period with respiratory protection. Plasma interleukin-6 increased (P < 0.0001) during both visits.
Conclusion:
Respiratory protection resulted in cross-shift inflammatory and respiratory reactions at return to unprotected work.

