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Updated: May 19, 2026

Occlusion of the Great and Small Saphenous Vein Using Copolymeric Glue Based on N-Butyl Cyanoacrylate and Methacryloxy Sulfolane
Published on: December 9, 2022
Glue therapy in hemoptysis: A new technique
Rakesh K Chawla1, Arun Madan, Dinesh Mehta
1Department of Respiratory Medicine, Critical Care and Sleep Medicine, Jaipur Golden Hospital, Rohini, New Delhi, India.
Intrabronchial glue instillation offers a safe and effective treatment for hemoptysis unresponsive to conventional therapies. This minimally invasive technique provides a viable alternative when advanced procedures like bronchial artery embolization are not feasible.
Area of Science:
- Pulmonology
- Interventional Bronchoscopy
Background:
- Hemoptysis, or spitting blood from the lungs, often requires advanced treatment.
- Many patients do not respond to conservative therapies like cough suppressants and antibiotics.
- Bronchial artery embolization (BAE) and surgery are advanced options but not always feasible.
Purpose of the Study:
- To evaluate a novel, cost-effective method for managing hemoptysis.
- To assess the safety and efficacy of intrabronchial glue instillation.
Main Methods:
- A therapeutic video bronchoscope (OLYMPUS T-180) was used for direct visualization.
- N-butyl cyanoacrylate glue was instilled via a polyethylene catheter through the bronchoscope's working channel.
- This procedure was performed as an alternative to BAE or surgery.
Main Results:
- Intrabronchial glue instillation was demonstrated as a cheap, effective, and safe alternative.
- The procedure was performed under direct vision using a video bronchoscope.
- This technique offers a potential solution for refractory hemoptysis.
Conclusions:
- Intrabronchial glue instillation is a promising treatment for hemoptysis.
- This method provides a safe and accessible alternative for patients unresponsive to standard treatments.
- The use of n-butyl cyanoacrylate via video bronchoscope offers a new therapeutic avenue.
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Assessment:
1. Clinical Evaluation:
History:

