Related Experiment Video
Updated: May 19, 2026

A Rat Dry Eye Model with Lacrimal Gland Dysfunction Induced by Scopolamine
Published on: February 9, 2024
Posttraumatic parotid fistula treated with transdermal scopolamine: a case report
Giulio Pagliuca1, Salvatore Martellucci, Chiara Rosato
1ENT Section, Department of Surgical Biotechnologies and Science, Sapienza University of Rome, 00185 Rome, Italy.
Abstract:
A parotid fistula is a rare and extremely unpleasant condition. In this paper, we present the case of a 53-year-old woman with a diagnosis of posttraumatic fistula of the parotid gland. After exclusion of other therapeutic alternatives, it was decided to use transdermal scopolamine patches at sustained release (Scopoderm TTS). This technique consists in the application every three days of a patch with 1.5 mg of scopolamine in the area of the mastoid apophysis; the patch releases a dose of 0.5 mg of the active substance over each 24-hour period. The patient underwent periodic clinical followup over a period of three years, achieving satisfactory results with no significant adverse effects.

