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Vasculitis with recurrent pulmonary hemorrhage in a long-term survivor after autologous bone marrow transplantation
M V Seiden1, W J O'Donnell, M Weinblatt
1Division of Clinical Oncology, Dana-Farber Cancer Institute, Boston, MA.
Abstract:
We report an unusual vasculitic syndrome in a long-term survivor of autologous bone marrow transplant. Clinical and pathologic studies revealed a cutaneous and pulmonary leukocytoclastic vasculitis complicated by recurrent pulmonary hemorrhage. Serologic studies revealed an elevated anti-neutrophil cytoplasmic antibody titer. The vasculitis has been successfully controlled with prednisone, cyclophosphamide, and trimethoprim/sulfamethoxazole.
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