Bullous systemic lupus erythematosus induced by UVB: report a case

Bullous systemic lupus erythematosus (BSLE) is a rare blistering disease that dramatically responds to dapsone administration without leaving any scar. Generally, those patients with BSLE meet the criteria for systemic lupus erythematosus, but some have a widespread vesiculobullous eruption only as an initial manifestation without any specific clinical or laboratory findings that fulfill the American College of Rheumatology diagnostic criteria for SLE. The authors report here a middle-aged female patient, whose diagnosis of BSLE was suspected at first from the characteristic vesiculobullous eruption, histopathology, immunofluorescent pattern, and positive antinuclear antibody, who was later confirmed to have UVB photosensitivity that induced the typical skin lesions.