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03:47
A Murine Model of Carotid Aneurysm Formation
Published on: September 9, 2025
Risk factors for multiple intracranial aneurysms rupture: a retrospective study
Hai-Tao Lu1, Hua-Qiao Tan, Bin-Xian Gu
1Institute of Interventional and Diagnostic Radiology, The Sixth Affiliated People's Hospital, Shanghai Jiao Tong University, No. 600, Yi Shan Road, Shanghai 200233, China.
Clinical Neurology and Neurosurgery
|August 28, 2012
Summary
Risk factors for ruptured multiple intracranial aneurysms were investigated. Middle-aged patients and anterior communicating artery aneurysms showed higher rupture risk, with smaller aneurysms also being prone to rupture.
Area of Science:
- Neurology
- Neurosurgery
- Radiology
Background:
- Predicting intracranial aneurysm rupture risk is controversial.
- Investigating risk factors for multiple intracranial aneurysms is crucial.
Purpose of the Study:
- To retrospectively analyze risk factors associated with the rupture of multiple intracranial aneurysms.
- To identify patterns in age, size, and location of ruptured multiple intracranial aneurysms.
Main Methods:
- Retrospective review of 134 patients with 294 aneurysms (July 2007-July 2011).
- Analysis using univariate and multivariate logistic regression models.
- Factors analyzed included age, gender, aneurysm site, and size.
Main Results:
- Aneurysm rupture incidence was significantly higher in patients aged 45-65 years.
- Anterior communicating artery (AComA) aneurysms had a significantly higher rupture rate (37.1%) compared to other sites.
- Most aneurysms (88.1%) were 5mm or less, with 68% of ruptured aneurysms also being 5mm or less.
Conclusions:
- Age, size, and location are key factors in managing unruptured intracranial aneurysms.
- AComA aneurysms in patients with multiple aneurysms are particularly prone to hemorrhage.
- Understanding these patterns aids in clinical decision-making for treatment.
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