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Updated: May 19, 2026

10:49
Antibiotic Dereplication Using the Antibiotic Resistance Platform
Published on: October 17, 2019
Abstract:
Activation/exploitation of biosynthetic pathways for useful metabolites is a major current interest. The metabolism remodeling approach developed by Craney and colleagues in this issue of (Chemistry & Biology), in which small molecule probes alter the secondary metabolites produced by streptomycetes, could lead to discovery of a multitude of novel antibiotics and other drugs.
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