Related Experiment Video
Updated: May 19, 2026
09:51
Laparoscopic Anterior Right Hepatectomy: A Single-Center Experience
Published on: December 4, 2023
Hepatic resection for primary hepatolithiasis: a single-center Western experience
Parissa Tabrizian1, Ghalib Jibara, Brian Shrager
1Mount Sinai Liver Cancer Program, Mount Sinai School of Medicine, New York, NY 10029, USA.
Journal of the American College of Surgeons
|August 28, 2012
Summary
Hepatic resection offers a safe and definitive treatment for primary hepatolithiasis (PHL), achieving excellent stone clearance and long-term results. The procedure is crucial given the high rate of co-occurring cholangiocarcinoma.
Area of Science:
- Hepatobiliary surgery
- Gastroenterology
- Surgical oncology
Background:
- Primary hepatolithiasis (PHL), or Oriental cholangiohepatitis, is increasingly diagnosed in Western countries.
- Treatment for PHL remains challenging, despite its rising incidence.
Purpose of the Study:
- To analyze the outcomes of patients undergoing hepatic resection (HR) for PHL at a single Western center.
- To evaluate the safety and efficacy of HR in managing PHL.
Main Methods:
- Retrospective review of 30 patients undergoing HR for PHL (1998-2012).
- Inclusion criteria: Child-Pugh class A liver function, no portal hypertension.
- Disease recurrence assessed via radiographic and clinical findings.
Main Results:
- 63.3% of patients had prior failed treatments; 23.3% had concomitant cholangiocarcinoma.
- Perioperative morbidity was 6.6%, with 0% mortality.
- Complete intrahepatic stone clearance achieved in all patients; 2 cholangiocarcinoma recurrences observed.
Conclusions:
- Hepatic resection is a safe and definitive treatment for PHL with excellent short- and long-term outcomes.
- The high incidence of cholangiocarcinoma supports resection of all involved hepatic segments.
