Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Cardiomyopathy I: Introduction and Classification01:25

Cardiomyopathy I: Introduction and Classification

Cardiomyopathy, or CMP, is a group of diseases affecting the myocardial structure, impairing its ability to pump blood effectively. This condition can lead to arrhythmias, heart failure, or sudden cardiac death.Cardiomyopathies are classified into primary and secondary categories:Primary Cardiomyopathy refers to conditions involving only the heart muscle that are often idiopathic (of unknown cause) or genetic. They primarily affect the myocardium without the involvement of other systemic...
Metastasis02:30

Metastasis

Metastasis is the spread of cancer cells from the original site to distant locations in the body. Cancer cells can spread via blood vessels (hematogenous) as well as lymph vessels in the body.
Epithelial-to-Mesenchymal Transition
The epithelial-to-mesenchymal transition or EMT is a developmental process commonly observed in wound healing, embryogenesis, and cancer metastasis. EMT is induced by transforming growth factor-beta (TGF-β) or receptor tyrosine kinase (RTK) ligands, which further...
Tumor Progression02:07

Tumor Progression

Tumor progression is a phenomenon where the pre-formed tumor acquires successive mutations to become clinically more aggressive and malignant. In the 1950s, Foulds first described the stepwise progression of cancer cells through successive stages.
Colon cancer is one of the best-documented examples of tumor progression. Early mutation in the APC gene in colon cells causes a small growth on the colon wall called a polyp. With time, this polyp grows into a benign, pre-cancerous tumor. Further...
Cancer02:18

Cancer

Cancers arise due to mutations in genes involved in the regulation of cell division, which leads to unrestricted cell proliferation. Modern science and medicine have made great strides in the understanding and treatment of cancer, including eradicating cancer in some patients. However, there is still no cure for cancer. This is largely due to the fact that cancer is a large group of many diseases.
Cardiomyopathy III: Hypertrophic Cardiomyopathy01:29

Cardiomyopathy III: Hypertrophic Cardiomyopathy

Hypertrophic cardiomyopathy, or HCM, is an autosomal dominant genetic disorder characterized by asymmetric left ventricular hypertrophy without ventricular dilation. It is more common in men and is typically diagnosed in young, athletic adults.EtiologyHCM is primarily genetic and is caused by mutations in genes encoding sarcomeric proteins. Researchers have identified over 1400 mutations across at least 11 different genes. Among these, the most frequently occurring mutations are found in the...
Cancers Originate from Somatic Mutations in a Single Cell02:21

Cancers Originate from Somatic Mutations in a Single Cell

Cancer arises from mutations in the critical genes that allow healthy cells to escape cell cycle regulation and acquire the ability to proliferate indefinitely. Though originating from a single mutation event in one of the originator cells, cancer progresses when the mutant cell lines continue to gain more and more mutations, and finally, become malignant. For example, chronic myelogenous leukemia (CML) develops initially as a non-lethal increase in white blood cells, which progressively...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Muscle-sparing thoracotomy: Anatomy and technique.

Multimedia manual of cardiothoracic surgery : MMCTS·2021
Same author

The impact of junior surgical jobs in cardiothoracic surgery on career choice in the United Kingdom.

General thoracic and cardiovascular surgery·2018
Same author

Perioperative detection of circulating tumour cells in patients with lung cancer.

Oncology letters·2017
Same author

Cardiac sarcoma causing mechanical tamponade: a radiological dilemma!

European heart journal·2015
Same author

The sweet sound of screening?

The Ulster medical journal·2013
Same author

Surgeon and haematologist: a review of comprehensive care for patients with inherited bleeding disorders in Northern Ireland.

International journal of surgery (London, England)·2012
Same journal

Association of liver dysfunction with outcomes after cardiac surgery-a meta-analysis.

Interactive cardiovascular and thoracic surgery·2022
Same journal

Extrapleural approach for thoracoabdominal infected aortic endograft: surgical and circulatory strategies.

Interactive cardiovascular and thoracic surgery·2022
Same journal

Retraction: Virtual reality-guided aortic valve leaflet reconstruction for type 0 bicuspid aortic stenosis.

Interactive cardiovascular and thoracic surgery·2022
Same journal

Continuous vagal intraoperative neuromonitoring during video-assisted thoracoscopic surgery for left lung cancer: its efficacy in preventing permanent vocal cord paralysis.

Interactive cardiovascular and thoracic surgery·2022
Same journal

Postoperative aortic injury caused by a staple line formed during wedge resection of the lung.

Interactive cardiovascular and thoracic surgery·2022
Same journal

Surgical management of cardiac cystic echinococcosis in a paediatric patient: a case report.

Interactive cardiovascular and thoracic surgery·2022
See all related articles

Related Experiment Video

Updated: May 19, 2026

Generation and Expansion of Primary, Malignant Pleural Mesothelioma Tumor Lines
08:01

Generation and Expansion of Primary, Malignant Pleural Mesothelioma Tumor Lines

Published on: April 21, 2022

Malignant primary cardiac tumours.

Nathan Burnside1, Simon W MacGowan

  • 1Department of Cardiothoracic Surgery, Royal Victoria Hospital, Belfast, UK. nburnside@doctors.net.uk

Interactive Cardiovascular and Thoracic Surgery
|August 28, 2012
PubMed
Summary
This summary is machine-generated.

Malignant heart tumors, specifically cardiac sarcoma, present rarely and lead to rapid patient deterioration. This review highlights management strategies and outcomes for these rare cardiac malignancies.

More Related Videos

Primary Orthotopic Glioma Xenografts Recapitulate Infiltrative Growth and Isocitrate Dehydrogenase I Mutation
09:43

Primary Orthotopic Glioma Xenografts Recapitulate Infiltrative Growth and Isocitrate Dehydrogenase I Mutation

Published on: January 14, 2014

Related Experiment Videos

Last Updated: May 19, 2026

Generation and Expansion of Primary, Malignant Pleural Mesothelioma Tumor Lines
08:01

Generation and Expansion of Primary, Malignant Pleural Mesothelioma Tumor Lines

Published on: April 21, 2022

Primary Orthotopic Glioma Xenografts Recapitulate Infiltrative Growth and Isocitrate Dehydrogenase I Mutation
09:43

Primary Orthotopic Glioma Xenografts Recapitulate Infiltrative Growth and Isocitrate Dehydrogenase I Mutation

Published on: January 14, 2014

Area of Science:

  • Cardiovascular Surgery
  • Oncology
  • Thoracic Medicine

Background:

  • Malignant heart tumors are rare, making their management a poorly investigated clinical area.
  • Primary cardiac tumors require specialized cardiothoracic expertise for diagnosis and treatment.

Observation:

  • A case series of three patients with cardiac sarcoma treated at a regional cardiothoracic center was reviewed.
  • Literature search of PubMed and Medline databases was conducted to supplement case review.

Findings:

  • Cardiac sarcoma is associated with rapid patient deterioration following initial presentation.
  • Management strategies for cardiac sarcoma require careful consideration due to the aggressive nature of the disease.

Implications:

  • Increased awareness and investigation into the management of cardiac sarcoma are crucial.
  • Early diagnosis and intervention may improve outcomes for patients with primary cardiac malignancies.