Related Experiment Video
Updated: May 19, 2026

Facile Preparation of Internally Self-assembled Lipid Particles Stabilized by Carbon Nanotubes
Published on: February 19, 2016
Nanoassemblies from homostructured polypeptides as efficient nanoplatforms for oral drug delivery
Yi Jia1, Yuan Tang, Hongmei He
1Department of Pharmaceutics, College of Pharmacy, Third Military Medical University, Chongqing 400038, China.
Abstract:
The assembly of homostructured polypeptides bearing various side groups into well-defined nanostructures was presented, with their size and topology mainly dominated by the chemical structure and molecular weight of peptides. Pharmacokinetic and pharmacodynamic studies based on rat models suggested these newly constructed nanoassemblies with low cytotoxicity may function as novel nanoplatforms to efficiently and safely deliver therapeutics to achieve better efficacy but lower side effects. Other applications in biomedical fields, such as biotechnology, medical imaging, and tissue engineering, may also be expected.
From The Clinical Editor:
This research team investigated the assembly of homostructured polypeptides bearing various side groups into well-defined nanostructures, and demonstrated low cytotoxicity in rat disease models, suggesting that these novel nanoplatforms may safely and efficiently deliver therapeutics with low side effects.
More Related Videos
06:57Rapid, Scalable Assembly and Loading of Bioactive Proteins and Immunostimulants into Diverse Synthetic Nanocarriers Via Flash Nanoprecipitation
Published on: August 11, 2018
05:08Solubility of Hydrophobic Compounds in Aqueous Solution Using Combinations of Self-assembling Peptide and Amino Acid
Published on: September 20, 2017
Related Concept Videos
Oral Drug Delivery Systems: Introduction
Site-Targeted Drug Delivery Systems: Polymeric Carriers
Factors Affecting Dissolution: Particle Size and Effective Surface Area
Oral Drug Delivery Systems: Delayed-Release Systems
Drug Delivery Systems: Different Types
Oral Drug Delivery Systems: Continuous-Release Systems