Celebrating Ruby: 40 years of NASSNANSCSNACCSNACC

W Andrew Kofke1

  • 1Departments of Anesthesiology and Critical Care and Neurosurgery, University of Pennsylvania, Philadelphia, PA 15213, USA. kofkea@uphs.upenn.edu

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The Ras Gene

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Ras is a superfamily...
The Ras Gene02:38

The Ras Gene

The Ras-gene-encoded proteins are regulators of signaling pathways controlling cell proliferation, differentiation, or cell survival. The Ras-gene family in humans constitutes three primary members—the HRas, NRas, and KRas. These genes code for four functionally distinct yet closely related proteins—the HRas, NRas, KRas4A, and KRas4B. The involvement of mutant Ras genes in human cancer was first discovered in 1982 and is among the most common causes of human tumorigenesis.
Ras is a superfamily...
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Nucleophilic Aromatic Substitution: Addition–Elimination (SNAr)

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Rous Sarcoma Virus (RSV) and Cancer

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The Nucleolus

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